Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984128 | 0.90 | TBXAS1 (0.42) | TBXAS1CDK2HTR2ASLC6A4KCNH2 | |
| SCHEMBL19983945 | 0.89 | TBXAS1 (0.41) | TBXAS1CDK2HTR2ASLC6A4KCNH2 | |
| SCHEMBL19983845 | 0.87 | TBXAS1 (0.44) | TBXAS1CDK2HTR2ASLC6A4KCNH2 | |
| SCHEMBL19983891 | 0.86 | GPR84 (0.49) | HTR2ASLC6A4HTR1ACHRNB2CHRNA7 | |
| SCHEMBL19984005 | 0.86 | HTR2A (0.44) | HTR2AMAPTNPSR1CHRNB2CHRNA7 | |
| SCHEMBL19983900 | 0.85 | CDK2 (0.42) | CDK2HTR1AGOT1TRPV1TRPA1 | |
| SCHEMBL19983867 | 0.84 | HTR2C (0.42) | HTR2ASLC6A4MEN1KMT2ALMNA | |
| SCHEMBL19984197 | 0.84 | GPR84 (0.49) | HTR2ASLC6A4KCNH2CHRNB2CHRNA7 | |
| SCHEMBL19983944 | 0.82 | GPR84 (0.40) | HTR2AHTTHTR1ACHRNB2CHRNA7 | |
| SCHEMBL19983854 | 0.82 | APP (0.39) | TBXAS1CDK2HTR2ASLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |