Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984194 | 0.91 | GPR84 (0.39) | GPR84CHRNB2CHRNA7CHRNA4P2RX3 | |
| SCHEMBL19983877 | 0.87 | GPR84 (0.36) | GPR84CHRNB2CHRNA7CHRNA4P2RX3 | |
| SCHEMBL19983800 | 0.87 | GPR84 (0.36) | GPR84CHRNB2CHRNA7CHRNA4P2RX3 | |
| SCHEMBL16626544 | 0.87 | GPR84 (0.36) | GPR84CHRNB2CHRNA7CHRNA4P2RX3 | |
| SCHEMBL19983764 | 0.86 | APP (0.38) | GPR84CHRNB2CHRNA7CHRNA4P2RX3 | |
| SCHEMBL19983943 | 0.82 | CYP3A4 (0.36) | GPR84CHRNB2CHRNA7CHRNA4CYP2D6 | |
| SCHEMBL19983771 | 0.81 | CHRNB2 (0.38) | GPR84CHRNB2CHRNA7CHRNA4P2RX3 | |
| SCHEMBL19983903 | 0.81 | CYP2D6 (0.39) | GPR84CHRNB2CHRNA7CHRNA4CYP2D6 | |
| SCHEMBL19983715 | 0.80 | HTR2A (0.42) | GPR84CHRNB2CHRNA7CHRNA4HTR2A | |
| SCHEMBL19984197 | 0.80 | GPR84 (0.49) | GPR84CHRNB2CHRNA7CHRNA4P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |