Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983854 | 0.89 | APP (0.39) | APPGPR84KCNH2LCKPGR | |
| SCHEMBL19983894 | 0.86 | GPR84 (0.39) | GPR84KCNH2HTR1ASLC6A4CHRNB2 | |
| SCHEMBL19983800 | 0.84 | GPR84 (0.36) | APPGPR84KCNH2HTR1ASLC6A4 | |
| SCHEMBL16626544 | 0.82 | GPR84 (0.36) | GPR84CHRNB2CHRNA7CHRNA4CYP2C9 | |
| SCHEMBL19983905 | 0.81 | GPR84 (0.45) | GPR84KCNH2SLC6A4CHRNB2CHRNA7 | |
| SCHEMBL19983945 | 0.81 | TBXAS1 (0.41) | GPR84KCNH2HTR1ASLC6A4TBXAS1 | |
| SCHEMBL19984194 | 0.79 | GPR84 (0.39) | GPR84HTR1ASLC6A4CHRNB2CHRNA7 | |
| SCHEMBL19983847 | 0.78 | TBXAS1 (0.42) | GPR84KCNH2HTR1ASLC6A4TBXAS1 | |
| SCHEMBL19984128 | 0.78 | TBXAS1 (0.42) | GPR84KCNH2HTR1ASLC6A4TBXAS1 | |
| SCHEMBL19983989 | 0.78 | GPR84 (0.46) | GPR84HTR1ACHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |