SCHEMBL19983979

SCHEMBL19983979

O=COc1cccc(Cl)c1C(Cl)Cl

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CXCL8 P10145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2095443 0.76 ALDH1A1 (0.43) MEN1ALDH1A1KMT2ATDP1LMNA
SCHEMBL54889 0.76 LMNA (0.47) MEN1ALDH1A1KMT2ATDP1LMNA
SCHEMBL28184037 0.73 ALDH1A1 (0.40) MEN1ALDH1A1KMT2ATDP1LMNA
SCHEMBL29068856 0.73 MRGPRX4 (0.41) MEN1ALDH1A1KMT2ATDP1LMNA
SCHEMBL19983998 0.73 ALDH1A1 (0.42) MEN1ALDH1A1KMT2ATDP1LMNA
SCHEMBL19979064 0.73 ALDH1A1 (0.39) MEN1ALDH1A1KMT2ALMNASMN1; SMN2
SCHEMBL5368610 0.72 CYP1A2 (0.45) MEN1ALDH1A1KMT2ATDP1LMNA
SCHEMBL19979063 0.69 ALDH1A1 (0.35) MEN1ALDH1A1KMT2ALMNACXCL8
SCHEMBL8667994 0.69 ALDH1A1 (0.48) MEN1ALDH1A1KMT2ATDP1LMNA
SCHEMBL1982757 0.68 TLR8 (0.45) MEN1ALDH1A1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10618872-B2 Process for preparing 3-chloro-2-vinylphenylsulfonates BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-04-14 US disclosed
EP-3265439-B1 PROCESS FOR PREPARING 3-CHLORO-2-VINYLPHENYLSULFONATES BAYER CROPSCIENCE AG (DE) 2019-03-27 EP disclosed
US-20180079717-A1 PROCESS FOR PREPARING 3-CHLORO-2-VINYLPHENYLSULFONATES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180079717-A1 PROCESS FOR PREPARING 3-CHLORO-2-VINYLPHENYLSULFONATES AGPS, VARS1, VPS4B MEN1 3202/4885ALDH1A1 3434/4885KMT2A 2164/4885
US-10618872-B2 Process for preparing 3-chloro-2-vinylphenylsulfonates AGPS, VARS1, VPS4B MEN1 3202/4885ALDH1A1 3434/4885KMT2A 2164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.