Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.46 |
| ▸ | MPO | P05164 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984128 | 0.89 | TBXAS1 (0.42) | GPR84HTR2AHTR1ACHRNB2CHRNA7 | |
| SCHEMBL19983905 | 0.88 | GPR84 (0.45) | GPR84HTR2ACHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984003 | 0.86 | GPR84 (0.50) | GPR84MPOHTR2AHTR1AALKBH5 | |
| SCHEMBL19984116 | 0.86 | CDK2 (0.44) | ARNR3C1 | |
| SCHEMBL19983891 | 0.85 | GPR84 (0.49) | GPR84MPOHTR2AHTR1AALKBH5 | |
| SCHEMBL19983758 | 0.84 | GPR84 (0.37) | GPR84MPOHTR2AALKBH5FTO | |
| SCHEMBL19984030 | 0.84 | GPR84 (0.48) | GPR84MPOHTR2AHTR1AALKBH5 | |
| SCHEMBL19983748 | 0.84 | GPR84 (0.50) | GPR84MPOHTR2AHTR1AALKBH5 | |
| SCHEMBL19984119 | 0.82 | GPR84 (0.53) | GPR84MPOHTR2AHTR1AALKBH5 | |
| SCHEMBL19983847 | 0.81 | TBXAS1 (0.42) | GPR84HTR2AHTR1ACHRNB2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |