Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 5/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | CCNK | O75909 | 3/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
| ▸ | CDK7 | P50613 | 2/20 | 0.34 |
| ▸ | CCNH | P51946 | 2/20 | 0.34 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983711 | 0.86 | CDK2 (0.40) | CDK2NR3C1NR3C2PGRBCHE | |
| SCHEMBL19983989 | 0.86 | GPR84 (0.46) | NR3C1AR | |
| SCHEMBL19984128 | 0.86 | TBXAS1 (0.42) | CDK2ARSLC6A4 | |
| SCHEMBL19983905 | 0.85 | GPR84 (0.45) | CNR2ARSLC6A4 | |
| SCHEMBL19984167 | 0.85 | NR3C1 (0.42) | CDK2NR3C1NR3C2PGRBCHE | |
| SCHEMBL19983952 | 0.84 | ABCC9 (0.40) | CDK2NR3C1NR3C2PGRBCHE | |
| SCHEMBL19983758 | 0.80 | GPR84 (0.37) | ARSLC6A4 | |
| SCHEMBL19983847 | 0.78 | TBXAS1 (0.42) | CDK2NR3C1NR3C2SLC6A4 | |
| SCHEMBL19983945 | 0.77 | TBXAS1 (0.41) | CDK2SLC6A4 | |
| SCHEMBL19983854 | 0.77 | APP (0.39) | CDK2NR3C1NR3C2PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |