Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983902 | 0.92 | MTNR1A (0.33) | MTNR1AMTNR1BP2RX7 | |
| SCHEMBL19983767 | 0.90 | — | — | |
| SCHEMBL19983901 | 0.83 | TSHR (0.35) | — | |
| SCHEMBL19983780 | 0.81 | PLK4 (0.30) | — | |
| SCHEMBL16626732 | 0.81 | HTR6 (0.39) | MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL16618668 | 0.80 | HTR6 (0.39) | MTNR1AMTNR1B | |
| SCHEMBL19983909 | 0.79 | SLC6A2 (0.35) | — | |
| SCHEMBL19984219 | 0.79 | SLC6A2 (0.36) | P2RX7 | |
| SCHEMBL19984114 | 0.79 | CYP1A2 (0.31) | — | |
| SCHEMBL19983907 | 0.78 | FPR1 (0.36) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |