Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.31 |
| ▸ | HTR2A | P28223 | 4/20 | 0.31 |
| ▸ | FADS1 | O60427 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984163 | 0.89 | FADS1 (0.36) | SLC6A2SLC6A3SLC6A4KCNH2HTR2A | |
| SCHEMBL19984171 | 0.87 | POLB (0.37) | SLC6A2SLC6A3MAPK14KDM4E | |
| SCHEMBL19983888 | 0.86 | P2RX7 (0.31) | SLC6A2SLC6A4KCNH2KDM4E | |
| SCHEMBL19983780 | 0.84 | PLK4 (0.30) | — | |
| SCHEMBL19983767 | 0.82 | — | — | |
| SCHEMBL19984114 | 0.82 | CYP1A2 (0.31) | — | |
| SCHEMBL19983733 | 0.81 | SLC6A2 (0.37) | SLC6A2SLC6A4 | |
| SCHEMBL19983907 | 0.81 | FPR1 (0.36) | SLC6A2MAPK14SLC6A4KCNH2HTR2A | |
| SCHEMBL19984029 | 0.81 | APP (0.35) | SLC6A4KCNH2HTR2A | |
| SCHEMBL19983902 | 0.81 | MTNR1A (0.33) | SLC6A2SLC6A3SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |