Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984027 | 0.93 | MAPK14 (0.37) | MEN1KMT2AMAPTMAPK14POLB | |
| SCHEMBL19984271 | 0.89 | HTR2A (0.34) | MEN1KMT2AMAPTKDRSLC6A4 | |
| SCHEMBL19983777 | 0.88 | ADRB2 (0.37) | MAPK14FBP1 | |
| SCHEMBL19983937 | 0.86 | MPO (0.37) | MEN1KMT2AMAPTSLC6A4KCNH2 | |
| SCHEMBL19984025 | 0.85 | MAPK14 (0.32) | MAPTMAPK14 | |
| SCHEMBL19983888 | 0.85 | P2RX7 (0.31) | SLC6A4KCNH2SLC6A2CYP1A2CYP2C8 | |
| SCHEMBL19984022 | 0.85 | AKR1C3 (0.38) | MAPTKDRALDH1A1MAPK14POLB | |
| SCHEMBL19984021 | 0.84 | GAK (0.40) | MEN1KMT2AKDRSLC6A4KCNH2 | |
| SCHEMBL19983901 | 0.84 | TSHR (0.35) | MEN1KMT2AMAPTSMN1; SMN2TP53 | |
| SCHEMBL19984127 | 0.84 | NUDT1 (0.36) | KDRSLC6A4KCNH2SLC6A2FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |