Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.43 |
| ▸ | SNCA | P37840 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984023 | 0.85 | HTR2A (0.47) | SLC6A2SLC6A4SLC6A3GPR84HTR2A | |
| SCHEMBL19983801 | 0.80 | GPR84 (0.41) | SLC6A2SLC6A4SLC6A3GPR84CYP3A4 | |
| SCHEMBL19984039 | 0.79 | GPR84 (0.50) | SLC6A2SLC6A4SLC6A3GPR84SNCA | |
| SCHEMBL19984035 | 0.78 | HTR2A (0.47) | GPR84SNCAKMT2AHTR2AKDM4E | |
| SCHEMBL19984044 | 0.78 | GPR84 (0.40) | GPR84CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11757398 | 0.77 | SLC6A4 (0.53) | LMNASLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL31415127 | 0.77 | GPR84 (0.72) | GPR84HTR2AHTR1ACHRNB2CHRNA7 | |
| SCHEMBL19983829 | 0.74 | HTR2A (0.44) | LMNASLC6A2SLC6A4SLC6A3GPR84 | |
| SCHEMBL19983951 | 0.73 | TRPV1 (0.41) | SLC6A4GPR84KMT2AHTR2AKDM4E | |
| SCHEMBL19983972 | 0.73 | GPR84 (0.40) | SLC6A2SLC6A4SLC6A3GPR84KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |