Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983976 | 0.86 | GPR84 (0.40) | GPR84ADORA2AADORA1CYP3A4CYP1A2 | |
| SCHEMBL19984023 | 0.81 | HTR2A (0.47) | GPR84CHRNB2CHRNA7CHRNA4ASH1L | |
| SCHEMBL19983801 | 0.81 | GPR84 (0.41) | GPR84CYP3A4CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983913 | 0.79 | GPR84 (0.38) | GPR84ADORA2AADORA1CHRNB2CHRNA7 | |
| SCHEMBL19984036 | 0.78 | LMNA (0.44) | GPR84CYP3A4CYP1A2CHRNB2CHRNA7 | |
| SCHEMBL19984039 | 0.77 | GPR84 (0.50) | GPR84MPOHTR2A | |
| SCHEMBL19983972 | 0.77 | GPR84 (0.40) | GPR84CYP3A4CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984035 | 0.77 | HTR2A (0.47) | GPR84CHRNB2CHRNA7CHRNA4ASH1L | |
| SCHEMBL19983829 | 0.76 | HTR2A (0.44) | GPR84CHRNB2CHRNA7CHRNA4ASH1L | |
| SCHEMBL19983815 | 0.74 | CYP2C9 (0.43) | GPR84CYP3A4CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |