Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.43 |
| ▸ | IDE | P14735 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR1F | P30939 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626419 | 0.87 | IDE (0.38) | HTR6IDEPDE4APDE4BPDE4C | |
| SCHEMBL16619142 | 0.87 | HTR6 (0.42) | HTR6IDEPDE4APDE4BPDE4C | |
| SCHEMBL28068083 | 0.87 | IDE (0.43) | HTR6IDEPDE4APDE4BPDE4C | |
| SCHEMBL19971473 | 0.87 | PDE4A (0.44) | HTR6IDEPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL16619139 | 0.87 | IDE (0.38) | HTR6IDEPDE4APDE4BPDE4C | |
| SCHEMBL28207663 | 0.85 | HTR6 (0.58) | HTR6IDEHTR1ADRD2HTR1D | |
| SCHEMBL16619000 | 0.85 | HTR6 (0.46) | HTR6IDEHTR1ADRD2HTR1D | |
| SCHEMBL16619172 | 0.85 | HTR6 (0.46) | HTR6IDEHTR1ADRD2HTR1D | |
| SCHEMBL19971346 | 0.85 | IDE (0.41) | HTR6IDEPDE4APDE4BPDE4C | |
| SCHEMBL16618718 | 0.85 | PDE4A (0.43) | HTR6IDEPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |