Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 8/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971349 | 0.90 | IDE (0.40) | IDEHTR6PDE4APDE4BPDE4C | |
| SCHEMBL19971357 | 0.89 | IDE (0.39) | IDEHTR6PDE4APDE4BPDE4C | |
| SCHEMBL19971359 | 0.87 | HTR6 (0.42) | IDEHTR6CHRNB4CHRNA3MEN1 | |
| SCHEMBL19984047 | 0.85 | HTR6 (0.43) | IDEHTR6PDE4APDE4BPDE4C | |
| SCHEMBL28068083 | 0.85 | IDE (0.43) | IDEHTR6PDE4APDE4BPDE4C | |
| SCHEMBL19971352 | 0.83 | PDE4A (0.42) | IDEHTR6PDE4APDE4BPDE4C | |
| SCHEMBL19971356 | 0.82 | IDE (0.37) | IDEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19971345 | 0.81 | IDE (0.43) | IDEHTR6PDE4APDE4BPDE4C | |
| SCHEMBL16619076 | 0.80 | HTR6 (0.47) | IDEHTR6PDE4APDE4BPDE4C | |
| SCHEMBL19971347 | 0.79 | POLB (0.37) | IDEHTR6PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |