Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 4/20 | 0.43 |
| ▸ | HTR6 | P50406 | 5/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068056 | 0.89 | IDE (0.42) | IDEHTR6PDE4APDE4BPDE4C | |
| SCHEMBL28068051 | 0.88 | IDE (0.41) | IDEHTR6PDE4APDE4BPDE4C | |
| SCHEMBL19984047 | 0.87 | HTR6 (0.43) | IDEHTR6PDE4APDE4BPDE4C | |
| SCHEMBL28068045 | 0.85 | HTR6 (0.42) | IDEHTR6CHRNB4CHRNA3NAMPT | |
| SCHEMBL19971346 | 0.85 | IDE (0.41) | IDEHTR6PDE4APDE4BPDE4C | |
| SCHEMBL16619076 | 0.80 | HTR6 (0.47) | IDEHTR6PDE4APDE4BPDE4C | |
| SCHEMBL19971345 | 0.79 | IDE (0.43) | IDEHTR6PDE4APDE4BPDE4C | |
| SCHEMBL16618718 | 0.79 | PDE4A (0.43) | IDEHTR6PDE4APDE4BPDE4C | |
| SCHEMBL16626645 | 0.77 | HTR6 (0.41) | IDEHTR6PDE4APDE4BPDE4C | |
| SCHEMBL19971473 | 0.77 | PDE4A (0.44) | IDEHTR6PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | claimed |
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | disclosed |