Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PKLR | P30613 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984110 | 0.87 | GPR84 (0.44) | MEN1KMT2AGPR84CFTRCHRNB2 | |
| SCHEMBL19983887 | 0.77 | GPR84 (0.43) | GPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984216 | 0.77 | GPR84 (0.48) | GPR84CFTRCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984197 | 0.76 | GPR84 (0.49) | GPR84CHRNB2CHRNA7CHRNA4P2RX3 | |
| SCHEMBL19983851 | 0.76 | CHRNB2 (0.47) | MEN1KMT2AGPR84CFTRCHRNB2 | |
| SCHEMBL19983983 | 0.76 | GPR84 (0.44) | GPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983741 | 0.74 | AKR1C3 (0.51) | MEN1KMT2AMAPTTDP1L3MBTL1 | |
| SCHEMBL19984193 | 0.74 | GPR84 (0.37) | GPR84CHRNB2CHRNA7CHRNA4P2RX3 | |
| SCHEMBL19983765 | 0.73 | GPR84 (0.43) | GPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984000 | 0.72 | HTR2A (0.46) | MEN1KMT2AGPR84CFTRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |