Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984119 | 0.87 | GPR84 (0.53) | HTR2ACHRNB2CHRNA7CHRNA4ALKBH5 | |
| SCHEMBL19984005 | 0.85 | HTR2A (0.44) | HTR2ACHRNB2CHRNA7CHRNA4PCSK9 | |
| SCHEMBL19984088 | 0.85 | HTR1D (0.50) | HTR2ACHRNB2CHRNA7CHRNA4GPR84 | |
| SCHEMBL19983831 | 0.85 | HTR2A (0.49) | HTR2APTGS2GPR84MEN1GAA | |
| SCHEMBL3281375 | 0.85 | HTR2A (0.61) | HTR2ACHRNB2CHRNA7CHRNA4PCSK9 | |
| SCHEMBL19983845 | 0.84 | TBXAS1 (0.44) | HTR2ACHRNB2CHRNA7CHRNA4GPR84 | |
| SCHEMBL19983715 | 0.83 | HTR2A (0.42) | HTR2ACHRNB2CHRNA7CHRNA4PCSK9 | |
| SCHEMBL19983754 | 0.83 | HTR2A (0.45) | HTR2ACHRNB2CHRNA7CHRNA4PCSK9 | |
| SCHEMBL19984216 | 0.83 | GPR84 (0.48) | HTR2ACHRNB2CHRNA7CHRNA4GPR84 | |
| SCHEMBL19983833 | 0.82 | SCN9A (0.44) | HTR2ACHRNB2CHRNA7CHRNA4GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |