Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984283 | 0.85 | HTR2A (0.47) | HTR2AGPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL3281375 | 0.82 | HTR2A (0.61) | HTR2AGPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983829 | 0.80 | HTR2A (0.44) | HTR2AGPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983715 | 0.78 | HTR2A (0.42) | HTR2AGPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983923 | 0.75 | GPR84 (0.51) | HTR2AGPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL23456044 | 0.73 | HTR1D (0.61) | HTR2AGPR84PCSK9FTOKDM4E | |
| SCHEMBL19984035 | 0.73 | HTR2A (0.47) | HTR2AGPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL15897700 | 0.72 | CHRNB2 (0.72) | HTR2AGPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984000 | 0.72 | HTR2A (0.46) | HTR2AGPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983776 | 0.71 | CHRNB2 (0.42) | HTR2AGPR84CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |