Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.51 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983837 | 0.78 | HSD17B1 (0.53) | — | |
| SCHEMBL19983776 | 0.77 | CHRNB2 (0.42) | GPR84CHRNB2CHRNA7CHRNA4HTR2A | |
| SCHEMBL19984170 | 0.75 | HTR2A (0.44) | GPR84ADRB3CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL31415117 | 0.75 | GPR84 (0.72) | GPR84HTR6SLC6A4HTR2A | |
| SCHEMBL19984287 | 0.74 | MAPT (0.45) | GPR84CHRNB2CHRNA7CHRNA4HTR2A | |
| SCHEMBL3281375 | 0.73 | HTR2A (0.61) | GPR84ADRB3CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984216 | 0.73 | GPR84 (0.48) | GPR84HTR6SLC6A4CHRNB2CHRNA7 | |
| SCHEMBL19984200 | 0.73 | ROCK2 (0.41) | GPR84HTR6CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983869 | 0.73 | MMP2 (0.46) | GPR84HTR6HTR2A | |
| SCHEMBL15897700 | 0.72 | CHRNB2 (0.72) | GPR84ADRB3SLC6A4CHRNB2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |