Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984200 | 0.82 | ROCK2 (0.41) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL19984287 | 0.77 | MAPT (0.45) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL19983953 | 0.77 | GPR84 (0.43) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL19983923 | 0.77 | GPR84 (0.51) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL3281375 | 0.74 | HTR2A (0.61) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL19983810 | 0.74 | ALKBH5 (0.39) | CHRNB2CHRNA7CHRNA4GPR84 | |
| SCHEMBL31415127 | 0.73 | GPR84 (0.72) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL15897700 | 0.73 | CHRNB2 (0.72) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL25356584 | 0.72 | PTPRA (0.58) | PIM1PIM3HTR2AKDM4EALDH1A1 | |
| SCHEMBL25356587 | 0.72 | PTPRA (0.58) | PIM1PIM3HTR2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |