Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.39 |
| ▸ | TTBK2 | Q6IQ55 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983833 | 0.89 | SCN9A (0.44) | HTR2ASLC6A4GPR84SCN9ACHRNB2 | |
| SCHEMBL19983734 | 0.88 | GPR84 (0.46) | HTR2ASLC6A4KCNH2GPR84TTBK1 | |
| SCHEMBL19983831 | 0.85 | HTR2A (0.49) | HTR2AGPR84 | |
| SCHEMBL19984216 | 0.84 | GPR84 (0.48) | HTR2ASLC6A4GPR84CHRNB2CHRNA7 | |
| SCHEMBL19984000 | 0.81 | HTR2A (0.46) | HTR2AGPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984119 | 0.80 | GPR84 (0.53) | HTR2AGPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984197 | 0.79 | GPR84 (0.49) | HTR2ASLC6A4KCNH2GPR84CHRNB2 | |
| SCHEMBL19984110 | 0.78 | GPR84 (0.44) | HTR2ASLC6A4KCNH2GPR84CHRNB2 | |
| SCHEMBL19983772 | 0.78 | GPR84 (0.48) | HTR2ASLC6A4KCNH2GPR84CHRNB2 | |
| SCHEMBL19984088 | 0.78 | HTR1D (0.50) | HTR2AGPR84CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |