Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983734 | 0.89 | GPR84 (0.46) | HTR2ASLC6A4MAPTGPR84HTR1A | |
| SCHEMBL19984180 | 0.89 | HTR2A (0.47) | SCN9AHTR2ASLC6A4GPR84CHRNB2 | |
| SCHEMBL19983831 | 0.86 | HTR2A (0.49) | HTR2AMEN1KMT2AMAPTGPR84 | |
| SCHEMBL19984000 | 0.82 | HTR2A (0.46) | HTR2AMEN1KMT2AMAPTGPR84 | |
| SCHEMBL19984119 | 0.81 | GPR84 (0.53) | HTR2AGPR84HTR1ACHRNB2CHRNA7 | |
| SCHEMBL19983869 | 0.81 | MMP2 (0.46) | HTR2AMEN1KMT2AMMP2MMP9 | |
| SCHEMBL19984088 | 0.79 | HTR1D (0.50) | HTR2AMEN1KMT2AMAPTGPR84 | |
| SCHEMBL19983845 | 0.78 | TBXAS1 (0.44) | HTR2ASLC6A4GPR84TRPV1HTR1A | |
| SCHEMBL19984002 | 0.78 | CHRNB2 (0.51) | MEN1KMT2AGPR84CHRNB2CHRNA7 | |
| SCHEMBL19984216 | 0.77 | GPR84 (0.48) | HTR2ASLC6A4GPR84KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |