Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 3/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983874 | 0.89 | CYP19A1 (0.33) | — | |
| SCHEMBL19983844 | 0.87 | ALDH1A1 (0.35) | CSF1RKITNAMPTJAK2PTK2 | |
| SCHEMBL19983840 | 0.85 | LRRK2 (0.36) | NAMPTJAK2PTK2 | |
| SCHEMBL19983743 | 0.85 | SRC (0.40) | SLC6A2SLC6A4KIT | |
| SCHEMBL19984203 | 0.85 | ABL1 (0.35) | KITNAMPT | |
| SCHEMBL19983721 | 0.84 | HTR2C (0.32) | NAMPT | |
| SCHEMBL19984171 | 0.83 | POLB (0.37) | SLC6A2NAMPT | |
| SCHEMBL19984127 | 0.83 | NUDT1 (0.36) | SLC6A2SLC6A4CYP1A2CYP2C19CYP11B1 | |
| SCHEMBL19983981 | 0.83 | CNR2 (0.34) | JAK2PTK2CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL19984199 | 0.83 | MAP3K8 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |