Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984007 | 0.91 | MAT2A (0.34) | ABL1P2RX7KDRMAT2ABCR | |
| SCHEMBL19983791 | 0.87 | KDR (0.33) | P2RX7KDRMAPT | |
| SCHEMBL19984009 | 0.87 | ALPL (0.37) | KDRNAMPT | |
| SCHEMBL19983981 | 0.86 | CNR2 (0.34) | KDRALDH1A1MEN1KMT2ADGAT2 | |
| SCHEMBL19983844 | 0.85 | ALDH1A1 (0.35) | NAMPTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL19984223 | 0.85 | SLC6A2 (0.32) | NAMPTKIT | |
| SCHEMBL19983915 | 0.83 | MKNK2 (0.35) | P2RX7MKNK2 | |
| SCHEMBL19983840 | 0.82 | LRRK2 (0.36) | NAMPT | |
| SCHEMBL16626439 | 0.82 | LMNA (0.39) | ABL1P2RX7KDRNAMPTSMN1; SMN2 | |
| SCHEMBL19983743 | 0.82 | SRC (0.40) | KDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |