Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | GAK | O14976 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983844 | 0.90 | ALDH1A1 (0.35) | MAPK14PTK2MEN1KMT2AKDM4E | |
| SCHEMBL19984132 | 0.89 | HDAC11 (0.31) | — | |
| SCHEMBL19984089 | 0.88 | METAP2 (0.32) | BUB1 | |
| SCHEMBL19984203 | 0.86 | ABL1 (0.35) | KDRMEN1KMT2AALDH1A1DGAT2 | |
| SCHEMBL19984007 | 0.84 | MAT2A (0.34) | KDRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19983856 | 0.83 | GRM4 (0.34) | CYP1A2CYP2C19 | |
| SCHEMBL19984271 | 0.83 | HTR2A (0.34) | CNR2MAPK14GAKKDRMEN1 | |
| SCHEMBL19984223 | 0.83 | SLC6A2 (0.32) | PTK2CYP1A2CYP3A4CYP2C19JAK2 | |
| SCHEMBL19983874 | 0.82 | CYP19A1 (0.33) | — | |
| SCHEMBL19983840 | 0.82 | LRRK2 (0.36) | PTK2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |