Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | LYN | P07948 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983957 | 0.89 | SLC6A4 (0.37) | ALDH1A1SLC6A4LYNBTK | |
| SCHEMBL19984306 | 0.85 | LCK (0.35) | SLC6A4 | |
| SCHEMBL16626663 | 0.79 | ALDH1A1 (0.40) | ALDH1A1SLC6A4NOTUM | |
| Hydrochloric Acid SCHEMBL16618976 | 0.79 | ALDH1A1 (0.40) | ALDH1A1SLC6A4NOTUM | |
| SCHEMBL19984171 | 0.78 | POLB (0.37) | ALDH1A1PIM1PIM2SGMS2 | |
| SCHEMBL19984281 | 0.76 | SLC6A4 (0.33) | SLC6A4 | |
| SCHEMBL19983826 | 0.75 | ABCG2 (0.37) | — | |
| SCHEMBL19983721 | 0.74 | HTR2C (0.32) | — | |
| SCHEMBL16626774 | 0.74 | SLC6A4 (0.36) | ALDH1A1SLC6A4LYNBTK | |
| SCHEMBL19984065 | 0.73 | P2RX7 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |