SCHEMBL19984281

SCHEMBL19984281

CNCc1cn(Sc2cccc(F)c2)c2cc(Nc3ccc(C)cc3OC(F)(F)F)cnc12

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.33
LCK P06239 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19984065 0.88 P2RX7 (0.34) LCK
SCHEMBL16626669 0.81 HTR6 (0.36) SLC6A4
Hydrochloric Acid SCHEMBL16619138 0.81 HTR6 (0.36) SLC6A4
SCHEMBL19984250 0.78 HTR2A (0.30) SLC6A4
SCHEMBL19984305 0.76 ALDH1A1 (0.41) SLC6A4
SCHEMBL19983957 0.76 SLC6A4 (0.37) SLC6A4
SCHEMBL19984306 0.74 LCK (0.35) SLC6A4LCK
SCHEMBL17971592 0.72 HTR6 (0.39) SLC6A4
SCHEMBL19983775 0.70 EGFR (0.34) LCK
SCHEMBL19983915 0.70 MKNK2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3052484-B1 SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME DAE WOONG PHARMA (KR) 2018-03-21 EP disclosed