Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 3/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984305 | 0.85 | ALDH1A1 (0.41) | SLC6A4 | |
| SCHEMBL16626778 | 0.80 | NAMPT (0.39) | LCKNAMPTDHODHATMNPC1 | |
| SCHEMBL19984171 | 0.79 | POLB (0.37) | NAMPTKDM4ESLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL16618946 | 0.79 | NAMPT (0.39) | LCKNAMPTDHODHATMNPC1 | |
| SCHEMBL19983733 | 0.79 | SLC6A2 (0.37) | NAMPTSLC6A2SLC6A4 | |
| SCHEMBL19983883 | 0.77 | HTR2C (0.32) | SLC6A2SLC6A4 | |
| SCHEMBL19983850 | 0.76 | LRRK2 (0.40) | SLC6A4SLC6A3 | |
| SCHEMBL19983736 | 0.74 | MAPT (0.38) | ATMKDM4EGAA | |
| SCHEMBL19983957 | 0.74 | SLC6A4 (0.37) | SLC6A4 | |
| SCHEMBL19984135 | 0.74 | BCL6 (0.40) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |