Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 11/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984281 | 0.88 | SLC6A4 (0.33) | LCK | |
| SCHEMBL16626777 | 0.82 | HTR6 (0.40) | P2RX7 | |
| Hydrochloric Acid SCHEMBL16618870 | 0.81 | HTR6 (0.41) | P2RX7 | |
| SCHEMBL19983791 | 0.79 | KDR (0.33) | P2RX7HCRTR1HCRTR2MAPT | |
| SCHEMBL19984203 | 0.78 | ABL1 (0.35) | P2RX7KITMEN1MAPTKMT2A | |
| SCHEMBL17971591 | 0.74 | HTR6 (0.46) | MEN1MAPTKMT2A | |
| SCHEMBL19983777 | 0.73 | ADRB2 (0.37) | P2RX7 | |
| SCHEMBL19984305 | 0.73 | ALDH1A1 (0.41) | — | |
| SCHEMBL19983915 | 0.73 | MKNK2 (0.35) | P2RX7 | |
| SCHEMBL19983957 | 0.73 | SLC6A4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |