Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.38 |
| ▸ | ITGAL | P20701 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984699 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL19984595 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MAPTRAB9AKDM4EKMT2A | |
| SCHEMBL21291444 | 0.76 | HCRTR1 (0.51) | ALDH1A1MAPK1KMT2A | |
| SCHEMBL29360904 | 0.76 | HCRTR1 (0.51) | ALDH1A1MAPK1KMT2A | |
| SCHEMBL19975023 | 0.73 | FKBP1A (0.48) | ALDH1A1MAPK1PKMRAB9AKMT2A | |
| SCHEMBL31343689 | 0.71 | MAPT (0.54) | ALDH1A1MAPK1MAPTPKMRAB9A | |
| SCHEMBL31343731 | 0.71 | MAPT (0.54) | ALDH1A1MAPK1MAPTPKMRAB9A | |
| SCHEMBL18814405 | 0.71 | MAPT (0.45) | ALDH1A1HPGDMAPK1MAPTPKM | |
| SCHEMBL7322642 | 0.70 | LTA4H (0.46) | ALDH1A1MAPTKMT2A | |
| SCHEMBL2905551 | 0.69 | SMN1; SMN2 (0.51) | ALDH1A1MAPTNPC1PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053157-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2018-03-22 | — | — | WO | disclosed |