Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984856 | 0.84 | CTSS (0.44) | GAAALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL19984853 | 0.84 | CTSS (0.44) | GAAALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL19984813 | 0.78 | KMT2A (0.42) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL19984787 | 0.78 | VDR (0.46) | ALDH1A1SMN1; SMN2HPGDTHRBKMT2A | |
| SCHEMBL19984971 | 0.78 | ADAMTS4 (0.45) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL18078745 | 0.76 | VSIR (0.48) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL19866358 | 0.76 | VSIR (0.48) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL19984807 | 0.73 | TP53 (0.43) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL19450458 | 0.73 | CTSS (0.45) | GAAALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL18078717 | 0.73 | CTSS (0.41) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |