Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GUSB | P08236 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984787 | 0.92 | VDR (0.46) | ADAMTS4ADAMTS5KDM4ELMNATP53 | |
| SCHEMBL18078745 | 0.80 | VSIR (0.48) | LMNAKMT2ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL19866358 | 0.80 | VSIR (0.48) | LMNAKMT2ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL19984853 | 0.79 | CTSS (0.44) | KDM4ELMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL19984856 | 0.79 | CTSS (0.44) | KDM4ELMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL19984813 | 0.79 | KMT2A (0.42) | LMNAKMT2ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL19984973 | 0.79 | CYP3A4 (0.46) | — | |
| SCHEMBL19984823 | 0.79 | ADAMTS4 (0.55) | ADAMTS4ADAMTS5KDM4ELMNAKMT2A | |
| SCHEMBL19984804 | 0.78 | GAA (0.45) | KDM4ELMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL19450458 | 0.78 | CTSS (0.45) | KDM4EKMT2ASMN1; SMN2MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |