SCHEMBL19984939

SCHEMBL19984939

CCOC(=O)/C(=C/OC1C=C(C)C(=O)O1)C1CCc2c1cccc2C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.38
CMA1 P23946 5/20 0.38
TDP1 Q9NUW8 2/20 0.35
NFE2L2 Q16236 3/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23877360 0.89 CMA1 (0.37) FFAR1CMA1NFE2L2
SCHEMBL21538770 0.89 NFE2L2 (0.37) FFAR1NFE2L2GAAKMT2ANPSR1
SCHEMBL19984944 0.83 NFE2L2 (0.38) TDP1NFE2L2ALDH1A1L3MBTL1
SCHEMBL19985033 0.82 FFAR1 (0.44) FFAR1CMA1TDP1KDM4EALDH1A1
SCHEMBL21538744 0.81 NFE2L2 (0.34) FFAR1NFE2L2KDM4EALDH1A1GAA
SCHEMBL19984938 0.80 FFAR1 (0.34) FFAR1NFE2L2L3MBTL1
SCHEMBL21538751 0.80 NFE2L2 (0.37) FFAR1NFE2L2KDM4EALDH1A1KMT2A
SCHEMBL21538717 0.79 NFE2L2 (0.36) NFE2L2KDM4EALDH1A1GAAKMT2A
SCHEMBL19985052 0.78 NFE2L2 (0.35) NFE2L2ALDH1A1GAAMAPK1KMT2A
SCHEMBL19985009 0.78 FFAR1 (0.40) FFAR1CMA1TDP1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512843-B1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-10-20 EP disclosed
US-11136292-B2 Plant growth regulator compounds SYNGENTA PARTICIPATIONS AG (CH) 2021-10-05 US disclosed
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2019-10-31 US disclosed
WO-2018050477-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11136292-B2 Plant growth regulator compounds FGF1, MST1, CDC20 FFAR1 2309/4885CMA1 3384/4885TDP1 4758/4885
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS FGF1, MST1, CDC20 FFAR1 2309/4885CMA1 3384/4885TDP1 4758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.