SCHEMBL19985052

SCHEMBL19985052

CCOC(=O)/C(=C/OC1C=C(C)C(=O)O1)C1CCOc2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 6/20 0.35
TSHR P16473 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
MAPK1 P28482 1/20 0.33
POLB P06746 2/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
MGAM O43451 1/20 0.32
AMY1A P0DUB6 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SSTR4 P31391 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21538699 0.90 L3MBTL1 (0.36) NFE2L2TSHRL3MBTL1NPSR1ALDH1A1
SCHEMBL23877358 0.88 NFE2L2 (0.37) NFE2L2PTGDR2SSTR4
SCHEMBL19984944 0.84 NFE2L2 (0.38) NFE2L2L3MBTL1ALDH1A1MAPT
SCHEMBL19985035 0.83 MGAM (0.34) TSHRL3MBTL1NPSR1ALDH1A1MAPT
SCHEMBL21538751 0.83 NFE2L2 (0.37) NFE2L2ALDH1A1MAPTMEN1KMT2A
SCHEMBL19984937 0.82 NFE2L2 (0.37) NFE2L2L3MBTL1ALDH1A1MAPTPOLB
SCHEMBL21538717 0.82 NFE2L2 (0.36) NFE2L2ALDH1A1MAPTGAAKMT2A
SCHEMBL19984894 0.81 NFE2L2 (0.40) NFE2L2L3MBTL1ALDH1A1MAPTPOLB
SCHEMBL21538770 0.81 NFE2L2 (0.37) NFE2L2L3MBTL1NPSR1GAAMEN1
SCHEMBL19985049 0.80 MEN1 (0.40) TSHRL3MBTL1NPSR1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512843-B1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-10-20 EP disclosed
US-11136292-B2 Plant growth regulator compounds SYNGENTA PARTICIPATIONS AG (CH) 2021-10-05 US disclosed
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2019-10-31 US disclosed
WO-2018050477-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11136292-B2 Plant growth regulator compounds FGF1, MST1, CDC20 NFE2L2 2365/4885TSHR 455/4885L3MBTL1 3472/4885
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS FGF1, MST1, CDC20 NFE2L2 2365/4885TSHR 455/4885L3MBTL1 3472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.