SCHEMBL23877360

SCHEMBL23877360

CC1=CC(O/C=C(/C(=O)O)C2CCc3c2cccc3C(F)(F)F)OC1=O

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CMA1 P23946 9/20 0.37
NFE2L2 Q16236 5/20 0.37
FFAR1 O14842 5/20 0.36
CTSG P08311 1/20 0.35
CYP2C8 P10632 1/20 0.35
CYP2C9 P11712 1/20 0.35
RBP4 P02753 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19984939 0.89 FFAR1 (0.38) CMA1NFE2L2FFAR1
SCHEMBL23877359 0.88 NFE2L2 (0.39) CMA1NFE2L2FFAR1
SCHEMBL23877351 0.82 NFE2L2 (0.40) NFE2L2
SCHEMBL21538770 0.77 NFE2L2 (0.37) NFE2L2FFAR1
SCHEMBL23877358 0.76 NFE2L2 (0.37) NFE2L2
SCHEMBL23877362 0.75 NFE2L2 (0.39) NFE2L2
SCHEMBL23877357 0.74 NFE2L2 (0.38) NFE2L2
SCHEMBL19984924 0.72 PIN1 (0.41) NFE2L2
SCHEMBL21538698 0.72 NFE2L2 (0.37) NFE2L2
SCHEMBL19984930 0.71 NFE2L2 (0.39) NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136292-B2 Plant growth regulator compounds SYNGENTA PARTICIPATIONS AG (CH) 2021-10-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11136292-B2 Plant growth regulator compounds FGF1, MST1, CDC20 CMA1 3384/4885NFE2L2 2365/4885FFAR1 2309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.