SCHEMBL19985050

SCHEMBL19985050

CCOC(=O)/C(=C/OC1OC(=O)C(C)=C1C)C1CCc2ccsc21

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.32
TDP1 Q9NUW8 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23877350 0.88
SCHEMBL19984922 0.83 PIN1 (0.37) MAPTL3MBTL1TDP1CYP4F2CYP4A11
SCHEMBL21538696 0.83 NFE2L2 (0.38) KDM4ECYP1A2CYP3A4GAAMAPT
SCHEMBL19984931 0.79 KMT2A (0.36) KDM4ECYP3A4MAPTCYP2C19
SCHEMBL19984936 0.78 KDM4E (0.34) KDM4EGAAMAPTCYP2C9
SCHEMBL19984890 0.78 KDM4E (0.39) KDM4ECYP1A2CYP3A4GAAMAPT
SCHEMBL21538720 0.78 ANO1 (0.37) KDM4EMAPT
SCHEMBL21538716 0.78 FFAR1 (0.35) CYP3A4GAAL3MBTL1
SCHEMBL19985043 0.78 HPGD (0.36) KDM4E
SCHEMBL23934431 0.76 KDM4E (0.33) KDM4ECYP1A2CYP3A4GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512843-B1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-10-20 EP disclosed
US-11136292-B2 Plant growth regulator compounds SYNGENTA PARTICIPATIONS AG (CH) 2021-10-05 US disclosed
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2019-10-31 US disclosed
WO-2018050477-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11136292-B2 Plant growth regulator compounds FGF1, MST1, CDC20 KDM4E 3400/4885CYP1A2 3770/4885CYP3A4 4655/4885
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS FGF1, MST1, CDC20 KDM4E 3400/4885CYP1A2 3770/4885CYP3A4 4655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.