SCHEMBL19985043

SCHEMBL19985043

CCOC(=O)/C(=C/OC1OC(=O)C(C)=C1C)C1CCCc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 6/20 0.36
ANO1 Q5XXA6 1/20 0.35
HTT P42858 2/20 0.35
XBP1 P17861 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PTGER4 P35408 1/20 0.35
CRBN Q96SW2 1/20 0.35
PRMT5 O14744 1/20 0.35
WDR77 Q9BQA1 1/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.34
TP53 P04637 1/20 0.34
FFAR1 O14842 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21538720 0.98 ANO1 (0.37) HPGDKDM4EALDH1A1ANO1HTT
SCHEMBL19984922 0.94 PIN1 (0.37) ALDH1A1ANO1
SCHEMBL23877353 0.88 ALDH1A1 (0.38) KDM4EALDH1A1HTTHSD17B10CRBN
SCHEMBL19984925 0.84 PIN1 (0.41) ALDH1A1ANO1HSD17B10
SCHEMBL21538751 0.83 NFE2L2 (0.37) HPGDKDM4EALDH1A1HTTXBP1
SCHEMBL21538716 0.83 FFAR1 (0.35) KMT2AMEN1FFAR1
SCHEMBL21538719 0.83 HPGD (0.38) HPGDKDM4EALDH1A1HTTXBP1
SCHEMBL19985035 0.83 MGAM (0.34) KDM4EALDH1A1KMT2AMEN1
SCHEMBL21538717 0.82 NFE2L2 (0.36) HPGDKDM4EALDH1A1ANO1HTT
SCHEMBL23877356 0.82 PIN1 (0.40) KDM4EALDH1A1ANO1HSD17B10CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512843-B1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-10-20 EP disclosed
US-11136292-B2 Plant growth regulator compounds SYNGENTA PARTICIPATIONS AG (CH) 2021-10-05 US disclosed
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2019-10-31 US disclosed
WO-2018050477-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11136292-B2 Plant growth regulator compounds FGF1, MST1, CDC20 HPGD 1966/4885KDM4E 3400/4885ALDH1A1 3543/4885
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS FGF1, MST1, CDC20 HPGD 1966/4885KDM4E 3400/4885ALDH1A1 3543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.