Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | FPR1 | P21462 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19988735 | 0.94 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1FPR1MAPK1LMNA | |
| SCHEMBL19985847 | 0.90 | DPP4 (0.45) | ALDH1A1MAPK1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL19985851 | 0.89 | FPR1 (0.45) | ALDH1A1L3MBTL1FPR1MAPK1LMNA | |
| SCHEMBL19972390 | 0.82 | FPR1 (0.49) | ALDH1A1L3MBTL1FPR1MAPK1LMNA | |
| SCHEMBL19972397 | 0.82 | FPR1 (0.49) | ALDH1A1L3MBTL1FPR1MAPK1LMNA | |
| SCHEMBL19972396 | 0.82 | FPR1 (0.49) | ALDH1A1L3MBTL1FPR1MAPK1LMNA | |
| SCHEMBL19985853 | 0.78 | FPR1 (0.51) | ALDH1A1L3MBTL1FPR1MAPK1LMNA | |
| SCHEMBL19985850 | 0.76 | DPP4 (0.51) | ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL755963 | 0.76 | DPP4 (0.52) | ALDH1A1L3MBTL1FPR1MAPK1LMNA | |
| SCHEMBL755965 | 0.76 | DPP4 (0.52) | ALDH1A1L3MBTL1FPR1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | FPR2, FPR1, FPR3 | ALDH1A1 3156/4885L3MBTL1 4536/4885FPR1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.