Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13461272 | 0.93 | KMT2A (0.52) | KMT2AL3MBTL1KDM1AMAOBPDE4B | |
| SCHEMBL13434397 | 0.93 | KMT2A (0.52) | KMT2AL3MBTL1KDM1AMAOBPDE4B | |
| SCHEMBL19985856 | 0.85 | L3MBTL1 (0.45) | KMT2AL3MBTL1PDE4BKCNA3MCHR1 | |
| SCHEMBL19985866 | 0.84 | KMT2A (0.46) | KMT2AL3MBTL1KDM1AMAOBPDE4B | |
| SCHEMBL19985863 | 0.84 | KMT2A (0.46) | KMT2AL3MBTL1KDM1AMAOBPDE4B | |
| SCHEMBL16780873 | 0.83 | KMT2A (0.52) | KMT2AL3MBTL1KDM1AMAOBPDE4B | |
| SCHEMBL13858621 | 0.83 | KMT2A (0.52) | KMT2AL3MBTL1KDM1AMAOBPDE4B | |
| SCHEMBL15716485 | 0.83 | KMT2A (0.52) | KMT2AL3MBTL1KDM1AMAOBPDE4B | |
| SCHEMBL13858620 | 0.83 | KMT2A (0.52) | KMT2AL3MBTL1KDM1AMAOBPDE4B | |
| SCHEMBL556530 | 0.83 | KMT2A (0.55) | KMT2AL3MBTL1MAOBKCNA3SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | FPR2, FPR1, FPR3 | KMT2A 3931/4885L3MBTL1 4536/4885KDM1A 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.