Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19988401 | 0.90 | KDM4E (0.37) | KDM4EGAAKMT2AALDH1A1TAAR1 | |
| SCHEMBL19985861 | 0.85 | KMT2A (0.38) | KDM4EKMT2AALDH1A1NPC1TP53 | |
| SCHEMBL19972236 | 0.80 | SMN1; SMN2 (0.40) | KDM4EGAAKMT2AALDH1A1NPC1 | |
| SCHEMBL158125 | 0.78 | ALDH1A1 (0.37) | KMT2AALDH1A1TAAR1RAB9ASMN1; SMN2 | |
| SCHEMBL19972227 | 0.76 | KMT2A (0.38) | KDM4EKMT2AALDH1A1NPC1TP53 | |
| SCHEMBL756201 | 0.70 | HTT (0.32) | GAAKMT2AALDH1A1TP53HSD17B10 | |
| SCHEMBL22609776 | 0.69 | PTGS2 (0.40) | KMT2AALDH1A1TAAR1HDAC1 | |
| SCHEMBL21342460 | 0.68 | KMT2A (0.44) | KDM4EGAAKMT2AALDH1A1TAAR1 | |
| SCHEMBL2042006 | 0.68 | ALDH1A1 (0.42) | KDM4EGAAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19972301 | 0.68 | ALDH1A1 (0.36) | KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | FPR2, FPR1, FPR3 | KDM4E 4525/4885GAA 3320/4885KMT2A 3931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.