Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30094487 | 0.88 | TAS1R3 (0.45) | TAS1R3TAS1R1ALDH1A1MEN1KMT2A | |
| SCHEMBL17290340 | 0.88 | TAS1R3 (0.45) | TAS1R3TAS1R1ALDH1A1MEN1KMT2A | |
| SCHEMBL16865531 | 0.81 | MT-CO2 (0.55) | TAS1R3TAS1R1BCHEACHEMEN1 | |
| SCHEMBL19926033 | 0.80 | LMNA (0.47) | TAS1R3TAS1R1ALDH1A1KMT2ACYP2C19 | |
| SCHEMBL29875423 | 0.80 | LMNA (0.47) | TAS1R3TAS1R1ALDH1A1KMT2ACYP2C19 | |
| SCHEMBL17290945 | 0.80 | CA12 (0.50) | ACHEALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL19926360 | 0.80 | TAS1R3 (0.47) | TAS1R3TAS1R1ALDH1A1MEN1KMT2A | |
| SCHEMBL23833631 | 0.79 | MT-CO2 (0.43) | ALDH1A1MEN1KMT2ABLMNPSR1 | |
| SCHEMBL803625 | 0.79 | TAS1R3 (0.46) | TAS1R3TAS1R1BCHEACHEALDH1A1 | |
| SCHEMBL30094600 | 0.79 | MT-CO2 (0.43) | ALDH1A1MEN1KMT2ABLMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079753-A1 | INHIBITORS OF CELLULAR METABOLIC PROCESSES | SERVIER PHARMACEUTICALS LLC | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079753-A1 | INHIBITORS OF CELLULAR METABOLIC PROCESSES | MNAT1, MAT2A, PCK2 | TAS1R3 4636/4885TAS1R1 4526/4885BCHE 4048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.