Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986532 | 0.78 | ADH1B (0.39) | HRH3 | |
| SCHEMBL18977628 | 0.77 | LATS1 (0.42) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL19986718 | 0.69 | ALDH1A1 (0.42) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL19986571 | 0.69 | ADH1B (0.34) | MAPT | |
| SCHEMBL5845349 | 0.67 | RAPGEF4 (0.52) | MAPTALDH1A1L3MBTL1 | |
| SCHEMBL5840516 | 0.67 | MAPT (0.44) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL23912766 | 0.67 | KDM4E (0.34) | HRH3MAPTHTT | |
| SCHEMBL7658960 | 0.67 | GAA (0.41) | HRH3MEN1KMT2AL3MBTL1 | |
| SCHEMBL10274903 | 0.65 | MAPT (0.46) | HRH3MAPTALDH1A1 | |
| SCHEMBL21230868 | 0.65 | GRIN2D (0.41) | HRH3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |