Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655803 | 0.83 | MAPK14 (0.40) | GAAPTGS2MAPK14PDK1PDK2 | |
| SCHEMBL7656019 | 0.83 | GAA (0.41) | GAAPTGS2MAPK14PDK1PDK2 | |
| SCHEMBL7658940 | 0.83 | GAA (0.45) | GAAPTGS2MAPK14PDK1PDK2 | |
| SCHEMBL7650705 | 0.82 | GAA (0.39) | GAAPTGS2MAPK14PDK1PDK2 | |
| SCHEMBL11662825 | 0.80 | MAPK14 (0.51) | GAAPTGS2MAPK14PDK1PDK2 | |
| SCHEMBL16301207 | 0.80 | SMN1; SMN2 (0.51) | GAAPTGS2MAPK14MEN1KMT2A | |
| SCHEMBL7656523 | 0.80 | PTGS2 (0.37) | GAAPTGS2MAPK14PDK1PDK2 | |
| SCHEMBL5840516 | 0.79 | MAPT (0.44) | L3MBTL1MEN1KMT2A | |
| SCHEMBL7655759 | 0.79 | ALDH1A1 (0.37) | GAAPTGS2MAPK14MEN1KMT2A | |
| SCHEMBL7656975 | 0.77 | GLA (0.44) | MAPK14LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340687-B1 | ELEVATE HIGH DENSITY LIPOPROTEIN CHOLESTEROL CONCENTRATION | AMERICAN HOME PRODUCTS CORPORATION | 2002-01-22 | — | — | US | disclosed |