SCHEMBL19986511

SCHEMBL19986511

Cc1cncc(C)c1NCC(C)CNC=O

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.38
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19986532 0.73 ADH1B (0.39) ADH1BADH1CADH1A
SCHEMBL13283251 0.72 ADH1B (0.68) ADH1BADH1CADH1A
SCHEMBL19986533 0.71 NUDT1 (0.33)
SCHEMBL19986536 0.69 AKT1 (0.31)
SCHEMBL19986715 0.68 KMT2A (0.41)
SCHEMBL19986647 0.67 AKT1 (0.30)
SCHEMBL19986571 0.65 ADH1B (0.34) ADH1BADH1CADH1A
SCHEMBL19986513 0.63 P2RX7 (0.33)
SCHEMBL5252227 0.62 TAAR1 (0.58) ADH1BADH1CADH1A
SCHEMBL5843068 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018050110-A1 NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR 正大天晴药业集团股份有限公司 2018-03-22 WO disclosed