SCHEMBL19986513

SCHEMBL19986513

Cc1cncc(Cl)c1NCC(C)(C)CNC=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 8/20 0.33
MAPT P10636 1/20 0.32
NUDT1 P36639 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19986533 0.90 NUDT1 (0.33) NUDT1
SCHEMBL19986571 0.77 ADH1B (0.34) P2RX7MAPT
SCHEMBL14746054 0.67 ADH1B (0.41)
SCHEMBL23981950 0.66 MAPT (0.42) P2RX7MAPT
SCHEMBL19986532 0.65 ADH1B (0.39)
SCHEMBL19986466 0.64 L3MBTL1 (0.36)
SCHEMBL19986511 0.63 ADH1B (0.38)
SCHEMBL19986538 0.62 KMT2A (0.60) MAPT
SCHEMBL19986541 0.61 HAO1 (0.33) MAPT
SCHEMBL270048 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018050110-A1 NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR 正大天晴药业集团股份有限公司 2018-03-22 WO disclosed