Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986692 | 0.93 | NAMPT (0.38) | KMT2APOLBMAPTKDM4EMEN1 | |
| SCHEMBL19986612 | 0.85 | RAB9A (0.45) | KMT2APOLBMAPTKDM4EMEN1 | |
| SCHEMBL19986717 | 0.77 | MEN1 (0.44) | KMT2AMAPTMEN1NPSR1CCR3 | |
| SCHEMBL19986708 | 0.75 | KDM4E (0.39) | KMT2AMAPTKDM4EMEN1CA12 | |
| SCHEMBL19986619 | 0.73 | NAMPT (0.37) | KMT2APOLBMAPTKDM4ENAMPT | |
| SCHEMBL19986611 | 0.72 | LMNA (0.50) | KMT2APOLBMAPTMEN1HTT | |
| SCHEMBL19986691 | 0.72 | LMNA (0.45) | KMT2AMAPTMEN1NPSR1CCR3 | |
| SCHEMBL19986718 | 0.70 | ALDH1A1 (0.42) | KMT2AMAPTKDM4EMEN1HTT | |
| SCHEMBL19986631 | 0.70 | KMT2A (0.53) | KMT2AMAPTMEN1NAMPTGAA | |
| SCHEMBL19986510 | 0.70 | LMNA (0.65) | KMT2AMAPTKDM4EMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |