Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | MARS1 | P56192 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986631 | 0.88 | KMT2A (0.53) | LMNARAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL19986700 | 0.86 | LMNA (0.53) | LMNATAAR1RAB9ANPC1L3MBTL1 | |
| SCHEMBL19986564 | 0.84 | NAMPT (0.52) | LMNARAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL19986554 | 0.84 | MEN1 (0.47) | LMNAKMT2ASMN1; SMN2NAMPTMEN1 | |
| SCHEMBL19986446 | 0.84 | KMT2A (0.49) | LMNARAB9ANPC1KMT2ATP53 | |
| SCHEMBL19986507 | 0.81 | KMT2A (0.38) | KMT2ATP53NAMPTMEN1EPHX2 | |
| SCHEMBL19986701 | 0.79 | MARS1 (0.59) | LMNATAAR1RAB9ANPC1L3MBTL1 | |
| SCHEMBL19986708 | 0.78 | KDM4E (0.39) | KMT2AMARS1NAMPTMEN1EPHX2 | |
| SCHEMBL5054174 | 0.74 | MARS1 (0.61) | LMNATAAR1RAB9ANPC1KMT2A | |
| SCHEMBL19986718 | 0.74 | ALDH1A1 (0.42) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |