Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986669 | 0.86 | MEN1 (0.48) | EPHX2KMT2AMEN1RAB9ASLC6A3 | |
| SCHEMBL19986566 | 0.86 | MEN1 (0.51) | EPHX2KMT2AMEN1ALDH1A1TP53 | |
| SCHEMBL19986446 | 0.86 | KMT2A (0.49) | EPHX2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL19986502 | 0.84 | KMT2A (0.60) | EPHX2KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL19986578 | 0.81 | MEN1 (0.41) | EPHX2KMT2AMEN1SLC6A3MAPT | |
| SCHEMBL19986530 | 0.80 | ALOX15 (0.58) | EPHX2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL19986563 | 0.79 | MEN1 (0.53) | EPHX2KMT2AMEN1TP53MAPT | |
| SCHEMBL19986445 | 0.79 | MEN1 (0.50) | KMT2AMEN1RAB9ATP53MAPT | |
| SCHEMBL19986564 | 0.79 | NAMPT (0.52) | EPHX2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL19986701 | 0.78 | MARS1 (0.59) | EPHX2KMT2AMEN1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |