Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATF1 | P18846 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986623 | 0.90 | MEN1 (0.45) | LMNARAB9AMEN1KMT2AMAPT | |
| SCHEMBL19986475 | 0.88 | RAB9A (0.50) | LMNARAB9AMEN1KMT2AMAPT | |
| SCHEMBL19986624 | 0.85 | LMNA (0.40) | LMNARAB9AMEN1KMT2AMAPT | |
| SCHEMBL19986463 | 0.85 | LMNA (0.60) | LMNARAB9AMEN1KMT2AMAPT | |
| SCHEMBL19986666 | 0.83 | LMNA (0.39) | LMNARAB9ACASRMEN1KMT2A | |
| SCHEMBL19986622 | 0.83 | NPC1 (0.51) | LMNARAB9ACASRMEN1KMT2A | |
| SCHEMBL19986714 | 0.80 | ALOX15 (0.43) | LMNARAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL19986465 | 0.79 | PRMT3 (0.38) | LMNARAB9AMEN1KMT2AMAPT | |
| SCHEMBL19986717 | 0.77 | MEN1 (0.44) | LMNARAB9AMEN1KMT2AMAPT | |
| SCHEMBL19986611 | 0.75 | LMNA (0.50) | LMNARAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429341-A | Novel capsid protein assembly inhibitors | 正大天晴药业集团股份有限公司 | 2021-09-24 | — | — | CN | disclosed |
| CN-109790123-B | Novel capsid protein assembly inhibitors | 正大天晴药业集团股份有限公司 | 2021-06-25 | — | — | CN | disclosed |
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |