Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ATF1 | P18846 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986531 | 0.90 | MEN1 (0.44) | PRMT3MAPTRAB9AP2RX7MEN1 | |
| SCHEMBL19986720 | 0.88 | RAB9A (0.49) | MAPTRAB9AMEN1KMT2APOLB | |
| SCHEMBL19986512 | 0.85 | MEN1 (0.54) | MAPTRAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL19986618 | 0.85 | MEN1 (0.38) | MAPTRAB9AP2RX7MEN1KMT2A | |
| SCHEMBL28574430 | 0.83 | NAMPT (0.47) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL19986726 | 0.79 | LMNA (0.39) | PRMT3MAPTRAB9AMEN1KMT2A | |
| SCHEMBL19986714 | 0.79 | ALOX15 (0.43) | RAB9AMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL19986466 | 0.78 | L3MBTL1 (0.36) | PRMT3RAB9AL3MBTL1FGFR3KDR | |
| SCHEMBL19986666 | 0.75 | LMNA (0.39) | MAPTRAB9APDE4DMEN1KMT2A | |
| SCHEMBL19986721 | 0.72 | RAB9A (0.45) | MAPTRAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |