SCHEMBL1998690

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7867834	0.83	NQO2 (0.56)	HTR1DHTR1BHTR1AKMT2AHTR2A
	SCHEMBL10582131	0.81	HPGD (0.56)	HPGDCYP2C19HTR1DHTR1BHTR1A
	SCHEMBL17872003	0.81	CYP2C19 (0.66)	HPGDCYP2C19HTR1DHTR1BHTR1A
	SCHEMBL6120510	0.78	HPGD (0.54)	HPGDCYP2C19HTR1DHTR1BHTR1A
	SCHEMBL2544150	0.78	HPGD (0.55)	HPGDCYP2C19HTR1AKMT2ACYP1A2
	SCHEMBL1121997	0.77	HTR1A (0.68)	HPGDCYP2C19HTR1DHTR1BHTR1A
	SCHEMBL7860320	0.77	HTR1F (0.50)	HTR1DHTR1BHTR1ACDK4CCND1
	Hydrochloric Acid SCHEMBL3869535	0.76	HTR1A (0.67)	HPGDCYP2C19HTR1DHTR1BHTR1A
	Hydrochloric Acid SCHEMBL7970523	0.76	HTR1A (0.67)	HPGDCYP2C19HTR1DHTR1BHTR1A
	SCHEMBL3194596	0.75	CDK4 (0.43)	HTR1DHTR1BCDK4CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.